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tlr4 blockade group  (MedChemExpress)


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    MedChemExpress tlr4 blockade group
    Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
    Tlr4 Blockade Group, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 609 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tlr4 blockade group/product/MedChemExpress
    Average 96 stars, based on 609 article reviews
    tlr4 blockade group - by Bioz Stars, 2026-05
    96/100 stars

    Images

    1) Product Images from "Dose-dependent IL-29 activation of TLR4 signalling drives eosinophil infiltration in chronic rhinosinusitis with nasal polyps"

    Article Title: Dose-dependent IL-29 activation of TLR4 signalling drives eosinophil infiltration in chronic rhinosinusitis with nasal polyps

    Journal: Acta Otorhinolaryngologica Italica

    doi: 10.14639/0392-100X-A1222

    Histological and molecular expression analysis of IL-29 and TLR4 in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
    Figure Legend Snippet: Histological and molecular expression analysis of IL-29 and TLR4 in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.

    Techniques Used: Expressing, Staining, Control, Immunohistochemical staining

    Effect of IL-29 on TLR4 and downstream signaling molecule activation. (A) Western blot analysis of TLR4 protein expression; (B) Western blot analysis of p-NF-κB protein expression; (C) Western blot analysis of p-MAPK protein expression. Eosinophils were stimulated with different concentrations of IL-29 (10, 25, 50, 100 ng/mL) for 24 hours. β-actin was used as the internal control. Data were obtained from 3 independent experiments. * indicates p < 0.05.
    Figure Legend Snippet: Effect of IL-29 on TLR4 and downstream signaling molecule activation. (A) Western blot analysis of TLR4 protein expression; (B) Western blot analysis of p-NF-κB protein expression; (C) Western blot analysis of p-MAPK protein expression. Eosinophils were stimulated with different concentrations of IL-29 (10, 25, 50, 100 ng/mL) for 24 hours. β-actin was used as the internal control. Data were obtained from 3 independent experiments. * indicates p < 0.05.

    Techniques Used: Activation Assay, Western Blot, Expressing, Control

    The interventional effect of TAK-242 Blocking TLR4 on IL-29 action. (A) Transwell assay showing changes in eosinophil migration after TLR4 blockade with TAK-242; (B) ELISA of IL-5 secretion after TAK-242 intervention; (C) ELISA of IL-13 secretion after TAK-242 intervention; (D) Western blot analysis of TLR4, p-NF-κB, and p-MAPK protein expression after TAK-242 treatment. Data are presented as mean ± SD. * indicates p < 0.05.
    Figure Legend Snippet: The interventional effect of TAK-242 Blocking TLR4 on IL-29 action. (A) Transwell assay showing changes in eosinophil migration after TLR4 blockade with TAK-242; (B) ELISA of IL-5 secretion after TAK-242 intervention; (C) ELISA of IL-13 secretion after TAK-242 intervention; (D) Western blot analysis of TLR4, p-NF-κB, and p-MAPK protein expression after TAK-242 treatment. Data are presented as mean ± SD. * indicates p < 0.05.

    Techniques Used: Blocking Assay, Transwell Assay, Migration, Enzyme-linked Immunosorbent Assay, Western Blot, Expressing



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    tlr4 blockade group  (MedChemExpress)
    96
    MedChemExpress tlr4 blockade group
    Histological and molecular expression analysis of IL-29 and <t>TLR4</t> in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.
    Tlr4 Blockade Group, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tlr4 blockade group/product/MedChemExpress
    Average 96 stars, based on 1 article reviews
    tlr4 blockade group - by Bioz Stars, 2026-05
    96/100 stars
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    Image Search Results


    Histological and molecular expression analysis of IL-29 and TLR4 in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.

    Journal: Acta Otorhinolaryngologica Italica

    Article Title: Dose-dependent IL-29 activation of TLR4 signalling drives eosinophil infiltration in chronic rhinosinusitis with nasal polyps

    doi: 10.14639/0392-100X-A1222

    Figure Lengend Snippet: Histological and molecular expression analysis of IL-29 and TLR4 in ECRSwNP. (A) Haematoxylin-eosin staining of the experimental and control groups; magnification 100×; (B) qPCR analysis of IL-29 and TLR4 mRNA expression and their correlation; (C) Correlation analysis of IL-29 and TLR4, showing a positive correlation in the experimental group (r = 0.6018, p < 0.0001); (D) Immunohistochemical expression of IL-29 in the experimental and control groups (D1: control group, 100×; D2: experimental group, 100×; D3: control group, 400×; D4: experimental group, 400×); (E) Immunohistochemical expression of TLR4 in the experimental and control groups (E1: control group, 100×; E2: experimental group, 100×; E3: control group, 400×; E4: experimental group, 400×). qPCR data are presented as mean ± SD, correlation analysis was performed using Pearson correlation coefficient, and p < 0.05 was considered statistically significant. Experimental group n = 30, control group n = 30.

    Article Snippet: To evaluate the role of TLR4 in IL-29-mediated eosinophil regulation, a TLR4 blockade group (IL-29 50 ng/mL + TAK-242 10 μM, MedChemExpress, HY-11109) and a TAK-242-only intervention group were established.

    Techniques: Expressing, Staining, Control, Immunohistochemical staining

    Effect of IL-29 on TLR4 and downstream signaling molecule activation. (A) Western blot analysis of TLR4 protein expression; (B) Western blot analysis of p-NF-κB protein expression; (C) Western blot analysis of p-MAPK protein expression. Eosinophils were stimulated with different concentrations of IL-29 (10, 25, 50, 100 ng/mL) for 24 hours. β-actin was used as the internal control. Data were obtained from 3 independent experiments. * indicates p < 0.05.

    Journal: Acta Otorhinolaryngologica Italica

    Article Title: Dose-dependent IL-29 activation of TLR4 signalling drives eosinophil infiltration in chronic rhinosinusitis with nasal polyps

    doi: 10.14639/0392-100X-A1222

    Figure Lengend Snippet: Effect of IL-29 on TLR4 and downstream signaling molecule activation. (A) Western blot analysis of TLR4 protein expression; (B) Western blot analysis of p-NF-κB protein expression; (C) Western blot analysis of p-MAPK protein expression. Eosinophils were stimulated with different concentrations of IL-29 (10, 25, 50, 100 ng/mL) for 24 hours. β-actin was used as the internal control. Data were obtained from 3 independent experiments. * indicates p < 0.05.

    Article Snippet: To evaluate the role of TLR4 in IL-29-mediated eosinophil regulation, a TLR4 blockade group (IL-29 50 ng/mL + TAK-242 10 μM, MedChemExpress, HY-11109) and a TAK-242-only intervention group were established.

    Techniques: Activation Assay, Western Blot, Expressing, Control

    The interventional effect of TAK-242 Blocking TLR4 on IL-29 action. (A) Transwell assay showing changes in eosinophil migration after TLR4 blockade with TAK-242; (B) ELISA of IL-5 secretion after TAK-242 intervention; (C) ELISA of IL-13 secretion after TAK-242 intervention; (D) Western blot analysis of TLR4, p-NF-κB, and p-MAPK protein expression after TAK-242 treatment. Data are presented as mean ± SD. * indicates p < 0.05.

    Journal: Acta Otorhinolaryngologica Italica

    Article Title: Dose-dependent IL-29 activation of TLR4 signalling drives eosinophil infiltration in chronic rhinosinusitis with nasal polyps

    doi: 10.14639/0392-100X-A1222

    Figure Lengend Snippet: The interventional effect of TAK-242 Blocking TLR4 on IL-29 action. (A) Transwell assay showing changes in eosinophil migration after TLR4 blockade with TAK-242; (B) ELISA of IL-5 secretion after TAK-242 intervention; (C) ELISA of IL-13 secretion after TAK-242 intervention; (D) Western blot analysis of TLR4, p-NF-κB, and p-MAPK protein expression after TAK-242 treatment. Data are presented as mean ± SD. * indicates p < 0.05.

    Article Snippet: To evaluate the role of TLR4 in IL-29-mediated eosinophil regulation, a TLR4 blockade group (IL-29 50 ng/mL + TAK-242 10 μM, MedChemExpress, HY-11109) and a TAK-242-only intervention group were established.

    Techniques: Blocking Assay, Transwell Assay, Migration, Enzyme-linked Immunosorbent Assay, Western Blot, Expressing